Halloween is just around the corner, and ghosts and ghouls will soon make an appearance at the door. However, nothing can send a shiver down the spine like leading a center-sized proposal for the first time. In this session, the Proposal Development Unit will focus on key considerations when approaching large, multidisciplinary proposals, including the expected time commitment as the principal investigator, team readiness/competitiveness, the timing and impact of your research idea and necessary resources for success.